Ulcerative Colitis

Cytokines and the JAK-STAT Pathway in UC*

Introduction

Find out more about the unique role of JAKs in cytokine
signalling, with detailed content and teaching materials on UC
pathogenesis.

Overview

Inflammatory
Pathways

Learn about UC
inflammatory pathways.

JAK-STAT Pathway

Discover the JAK-STAT pathway in UC.

JAK Pairings

Find out more about JAK pairings in UC.

JAK-STAT Function 

Find out why the JAK-STAT pathway is of particular therapeutic interest in UC.

JAK, Janus kinase; STAT, signal transducer and activator of transcription; UC, ulcerative colitis.

* Note that some of the information contained in this section pertains to preclinical studies in mice.